Staff
| Personal Information | ||
| Name | Radomski, Marek | |
| College Address | Pharmacy and Pharmaceutical Sciences, East End Development 4/5 |
|
| Main Department | School of Pharmacy | |
| College Title | Chair of Pharmacology (1979) | |
| marek.radomski@tcd.ie | ||
| College Tel | +353 1 896 2819 | |
| Biography | |
| Born in Bochnia, Poland. High School: Liceum Jana Matejki in Wieliczka, Poland. A medical graduate of College of Medicine Jagiellonski University in Krakow, Poland. PhD in pharmacology from College of Medicine Jagiellonski University. A highly-cited pharmacologist (listed in www.isihighlycited.com, 14,560 citations to date by Google Scholar) who worked both in academia and pharmaceutical industry in Poland (Jagiellonski University in Krakow and Polish Academy of Sciences in Warsaw), UK (Wellcome Research Laboratories in Beckenham), Spain (Lacer SA in Barcelona), Canada (University of Alberta in Edmonton) and USA (University of Texas in Houston. He joined School of Pharmacy and Pharmaceutical Sciences Trinity College Dublin in 2006 as Professor and Chair of Pharmacology. He served as Director of Research in School of Pharmacy and currently serves as Head of School and ProDean Faculty of Health Sciences Trinity College Dublin. He contributed to undergraduate teaching of medical,dentistry, nursing and pharmacy students in Europe, Canada and USA. He mentored many MSc, PhD students, as well as post-doctoral researchers. When at Trinity he graduated four PhD students and presently is supervising three PhD students. | |
| Professional Qualifications | |
| Qualification | Institution | Class of Degree | Title of Dissertation | Date Conferred |
| M.D. (Honours with Distinction) | Jagiellonski University, Krakow, Poland | 1978 | ||
| Ph.D. | Jagiellonski University, Krakow, Poland | 1983 | ||
| Doctor of Science | Polish Academy of Sciences | 1990 | ||
| Masters in Artibus | Trinity College Dublin | 2006 |
| Representations |
| Details | Date |
| Panels: Planing and Priorities Committee, Perinatal Research Centre, University of Alberta Curriculum Innovation Committee, Medical Faculty University of ALberta Health Sciences Animal Welfare Committee, Graduate Study Executive Committee, Department of Pharmacology University of Alberta Clinical Research Working Group, University of Alberta Medical Resident Research Evaluation Panel, University of Alberta Medical Student Admission Committee, National Institute of Health (USA), Special Emphasis Panel of the Womenm's Health RFA Canadian Institute of Health Research: University-Industry Committee(scientific officer) Bayer-CBS-Hema-Quebec-Canadian Institutes of Health Research Partnership Fund (scientific officer), Canadian Institute of Health Research: New Investigators Award Committee Canadian Institutes of Health Research: Proof of Principle Studies, Canadian Institutes of Health Research CIHR/Rx&D Collaborative Research Chair Program (scientific officer). | |
| Phytopharm (UK) | |
| Enterprise Ireland | |
| Netherlands Heart Foundation | |
| Biotechnology and Biological Sciences Research Council (UK) | |
| Administrative Functions | |
| Details | Level | Date From | Date To |
| Professor and Chair of Pharmacology, School of Pharmacy, Trinity College Dublin, Ireland | 2006 | ||
| Director of Research School of Pharmacy | 2007 | 2008 | |
| Principal Investigator, Centre for Research on Adaptive Nanostructures and Nanodevices | 2007 | ||
| Head of School od Pharmacy and Pharmaceutical Sciences | 2008 | ||
| ProDean Faculty of Health Sciences Trinity College | 2009 |
| Membership of Professional Institutions, Associations, Societies |
| Details | Date From | Date To |
| World Innovation Foundation | 2005 |
| Awards and Honours | |
| Award | Date |
| Alberta Heritage Foundation for Medical Research Scholar | 1994-2000 |
| Canadian Insititutes of Health Research Scientist | 1999-2002 |
| University of Alberta McCalla Research Professorship | 1999-2000 |
| Canadian Pharmacological Society Alta-Pharm International Senior Scientist Award | 2001 |
| State Professorship presented by President of the Republic of Poland | 2002 |
| More Awards and Honours>>> | |
| Education Details | |
| School/College | Date From | Date To |
| Jagiellonski University Krakow, Poland | 1972 | 1978 |
| Languages |
| Language | Skill Reading | Skill Writing | Skill Speaking |
| English | Fluent | Fluent | Fluent |
| French | Medium | Medium | Medium |
| Polish | Fluent | Fluent | Fluent |
| Russian | Medium | Medium | Medium |
| Employment Details | |
| Position Held | Job Description | Where | Date From | Date To |
| Research Associate | Department of Pharmacology, Medical School Jagiellonian University | 1978 | 1981 | |
| Lecturer | Department of Pharmacology Medical School Jagiellonski University | 1981 | 1987 | |
| Senior Lecturer | Polish Academy of Sciences Warsaw, Poland | 1987 | 1991 | |
| Senior Scientist | Wellcome Research Laboratories, Beckenham, U.K. | 1989 | 1993 | |
| Head Nitric Oxide Research Group | Wellcome Research Laboratories, Beckenham, U.K. | 1993 | 1994 | |
| More Employment Details>>> | ||||
| Description of Research Interests |
| 1. Nanopharmacology, nanoparticles and nanotoxicology. 2. Mechanisms regulating haemostatic and non-haemostatic functions of platelets. 3. Biology and pharmacology of nitric oxide and matrix metalloproteinases. 4. Extracorporeal circulation. |
| Research Interests | |||
| Angiogenesis | Asthma, Cystic Fibrosis, obstructive airways, interstitial lung diseases, pulmonary fibrosis | Breast cancer | Cardiovascular and molecular pharmacology |
| Coronary artery ischaemia | Cytokines, Nitric Oxide | Drug discovery, profiling, targeting | Haemotology |
| Inflammation | NANOBIOTECHNOLOGY | Nanomedicine | Pharmacology |
| Pharmacy | Thrombosis and haemostasis | Vascular Biology, Thrombosis |
| Research Projects | |
| Project title | Nanopharmacology in platelet research: focus on nitric oxide and matrix metalloproteinases |
| Summary | |
| Funding Agency | Science Foundation Ireland |
| Programme | SFI Investigator Programme |
| Type of Project | |
| Date from | 2006 |
| Date to | 2100 |
| Person Months | |
| Project title | BioNanoInteract |
| Summary | |
| Funding Agency | SFI |
| Programme | Strategic Research Cluster |
| Type of Project | |
| Date from | 2007 |
| Date to | 2010 |
| Person Months | |
| Project title | Preclinical Development od Aspirin-based drugs |
| Summary | |
| Funding Agency | Enterprise Ireland |
| Programme | Technology Development Phase |
| Type of Project | |
| Date from | 2007 |
| Date to | 2009 |
| Person Months | |
| Publications |
| Peer Reviewed |
| Jun Wang, Carlos Medina, Marek W. Radomski, John F. Gilmer, N-subsituted homopiperazine barbiturates as gelatinase inhibitors, Bioorganic & Medicinal Chemistry, 19, (16), 2011, p4985-4999 Url TARA - Full Text DOI |
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| Santos-Martinez, MJ, Medina, C, Prina-Mello, A, Conroy, J, Samuels, SP, Volkov, Y, Radomski, MW, A nanoscale resolution assay of flow-induced platelet microaggregation, Kardiochirurgia i Torakochirurgia Polska, 7, (4), 2010, p365-375 | |
| Gaffney, A.M., Wildhirt, S.M., Griffin, M.J., Annich, G.M., Radomski, M.W., Extacorporeal life support, British Medical Journal, 341, 2010, c5317 Notes: [PubMed ID: 21045023] DOI |
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| Jones, M., Inkielewicz, I., Medina, C., Santos-Martinzez, M.J., Radomski, M.W., Radomski, A., Lally, M.N., Moriarty, L.M., Gaynor, J., Carolan, C.G., Coyne, D., O'Byrne, P., Clancy, J.M., Gilmer, J.F. , Isosorbide-based aspirin prodrugs: integration of nitric oxide releasing groups. , Journal of Medicinal Chemistry, 52, (21), 2009, p6588-6598 Notes: [PubMed ID: 19821574] DOI |
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| More Publications>>> | |